Enlarge / A boy smiles as he gets a measles, mumps, and rubella (MMR) vaccination. (credit: Getty | Robyn Beck )

State health departments are facing federal budget cuts to programs that support childhood vaccination, which are coming at a time when immunization rates among children are slipping and under threat from anti-vaccine rhetoric.

News of the budget cuts was first reported by KFF Health News , which obtained a Centers for Disease Control and Prevention email dated June 27 that informed states of future funding reductions. The email, addressed to state immunization managers and signed by two CDC officials, said that the cuts will be "a significant change to your budget."

"There will be no easy solution for this," the CDC email read. "We know that this change will require some tough decisions."

Enlarge (credit: Zach Gibson/Getty Images)

Three landmark Supreme Court decisions in 2022 have each been widely criticized by health experts as threats to public health, but a study released Thursday in JAMA Network Open modeled their collective toll. The study found that, by conservative estimates, the decisions will lead to thousands of deaths in the coming years, with tens of thousands more being harmed.

The three decisions included: one from January 13, 2022, that invalidated some COVID-19 workplace protections ( National Federation of Independent Business v Department of Labor, Occupational Safety and Health Administration (OSHA) ); one on June 23, 2022, that voided some state laws restricting handgun carry ( New York State Rifle and Pistol Association Inc v Superintendent of New York State Police (Bruen) ); and one on June 24, 2022, that revoked the constitutional right to abortion ( Dobbs v Jackson Women’s Health Organization ).

A group of health researchers, led by Adam Gaffney at Harvard University, modeled how these decisions would impact Americans' morbidity and mortality in the near future.

Enlarge / The Centers for Disease Control and Prevention (CDC) headquarters stands in Atlanta, Georgia, on Saturday, March 14, 2020. (credit: Getty | Bloomberg )

The tally of COVID-19 cases linked to a conference of disease detectives hosted by the Centers for Disease Control and Prevention in April has reached at least 181, the agency reported .

Roughly 1,800 gathered in person for this year's annual Epidemic Intelligence Service (EIS) Conference, which was held on April 24 to 27 in a hotel conference facility in Atlanta where the CDC's headquarters are located. It was the first time the 70-year-old conference had in-person attendees since 2019. The CDC agency estimates an additional 400 attended virtually this year.

By the last day of the event, a number of in-person attendees had reported testing positive for COVID-19, causing conference organizers to warn attendees and make changes to reduce the chance of further spread. That reportedly included canceling an in-person training and offering to extend the hotel stays of sick attendees who needed to isolate.

Enlarge / Heart scan. (credit: Getty | BSIP )

The mRNA-based COVID-19 vaccines have proven remarkably safe and effective against the deadly pandemic. But, like all medical interventions, they have some risks. One is that a very small number of vaccinated people develop inflammation of and around their heart—conditions called myocarditis, pericarditis, or the combination of the two, myopericarditis. These side effects mostly strike males in their teens and early 20s, most often after a second vaccine dose. Luckily, the conditions are usually mild and resolve on their own.

With the rarity and mildness of these conditions, studies have concluded, and experts agree that the benefits of vaccination outweigh the risks—male teens and young adults should get vaccinated. In fact, they're significantly more likely to develop myocarditis or pericarditis from a COVID-19 infection than from a COVID-19 vaccination. According to a large 2022 study led by researchers at Harvard University and the Centers for Disease Control and Prevention, the group at highest risk of myocarditis and pericarditis after vaccination—males aged 12 to 17—saw 35.9 cases per 100,000 (0.0359 percent) after a second vaccine dose, while the rate was nearly double after a COVID-19 infection in the same age group, with 64.9 cases per 100,000 (0.0649 percent)

Still, the conditions are a bit of a puzzle. Why do a small few get this complication after vaccination? Why does it seem to solely affect the heart? How does the damage occur? And what does it all mean for the many other mRNA-based vaccines now being developed?

Enlarge / Florida surgeon general Joseph Ladapo speaks at a press conference. (credit: Getty | Paul Hennessy )

Florida health officials deleted key data and statistics from a state analysis on the safety of mRNA COVID-19 vaccines, falsely making them appear unsafe for young men, according to draft versions of the analysis obtained by the Tampa Bay Times through public records requests .

The final analysis, which was widely criticized for its poor quality and dubious conclusions , was the basis for a statewide recommendation by Surgeon General Joseph Ladapo last October that young men, ages 18 to 39, should not receive an mRNA COVID-19 vaccine. The analysis—posted on the Florida Department of Health's website with no authors listed—claimed to find "an 84% increase in the relative incidence of cardiac-related death among males 18-39 years old within 28 days following mRNA vaccination."

Ladapo, who has a history of fearmongering about COVID-19 vaccines , touted the analysis, saying in a press release at the time that "these are important findings that should be communicated to Floridians.”

Enlarge / Giant panda cub Huanlili plays with a bamboo during her first birthday at the Beauval zoological park in Saint-Aignan, central France, on August 2, 2022. (credit: Getty | GUILLAUME SOUVANT )

Chinese scientists have published their long-awaited genetic analysis of the samples and swabs they collected in early 2020 from the Huanan Seafood Market, the initial epicenter of the pandemic.

In the study , published Wednesday in Nature, the authors acknowledge for the first time that wildlife susceptible to SARS-CoV-2 infection—including raccoon dogs —were present in the market amid the plethora of genetic traces from SARS-CoV-2 and humans. But, the overall analysis is flawed, indicating the presence of animals that were almost certainly not at the market, including giant pandas, chimpanzees, and Atlantic grey seals. The authors continued to downplay the potential that a virus spillover from wildlife to humans in the crowded market was the spark that ignited the pandemic. Instead, they repeatedly put forward, without evidence, hypotheses favored by Chinese officials, namely that the virus was carried into the market via humans or frozen foods, and the bustling venue became an amplifier site for infection.

Still, the publication of the data is momentous—and a long time coming. Though the samples were collected from January 1 to March 30 of 2020, a draft of the study and some of the data were only first released in a preprint two years later, in February 2022. The preprint reported that SARS-CoV-2 was abundant amid human genetic material from the samples, indicating that the virus was prevalent among people at the market before it was shuttered on the morning of January 1. The authors, led by scientists at China's Centers for Disease Control and Prevention (China CDC), noted that they had also tested some animals in the market—mostly rabbits, stray cats, and snakes—but all were negative for SARS-CoV-2.

Enlarge / A vial containing Moderna COVID-19 booster vaccine at a vaccination center. (credit: Getty | SOPA Images )

A vaccine advisory group for the World Health Organization said Tuesday that, at this point, it does not recommend additional, let alone annual COVID-19 booster shots for people at low to medium risk of severe disease. It advised countries to focus on boosting those at high risk—including older people, pregnant people, and those with underlying medical conditions—every six to 12 months for the near- to mid-term.

The new advice contrasts with proposed plans by US Food and Drug Administration , which has suggested treating COVID-19 boosters like annual flu shots for the foreseeable future. That is, agency officials have floated the idea of offering updated formulations each fall, possibly to everyone, including the young and healthy.

In a viewpoint published last May in JAMA , the FDA's top vaccine regulator, Peter Marks, along with FDA Commissioner Robert Califf and Principal Deputy Commissioner Janet Woodcock, argued that annual COVID booster campaigns in the fall, ahead of winter waves of respiratory infections—such as flu, COVID-19, and RSV—would protect health care systems from becoming overwhelmed. And they specifically addressed the possibility of vaccinating those at low risk.

Enlarge / A person wearing a tinfoil hat on September 20, 2019. (credit: Getty | Bridget Bennett )

In the latest efforts by Republican lawmakers to enshrine into law Americans' right to freely spread deadly infectious diseases to each other, the Missouri House this week advanced a bill that would bar governments, schools, and employers from mandating certain vaccines—as well as things like vaccine microchips, which do not exist.

The bill, HB 700 ( PDF ), was sponsored by Rep. Bill Hardwick, a Republican from Waynesville. Hardwick told the St. Louis Post-Dispatch that he believed people " lost their minds " during the COVID-19 pandemic, and that legally barring officials and employers from requiring life-saving vaccination, even among health care workers, feels "like it's the right thing to do."

The bill specifically bars requirements for people to receive COVID-19 vaccines. But it doesn't stop there. It also bars any requirements for people to receive "a dose of messenger ribonucleic acid (mRNA)," thus barring requirements for any future mRNA-based vaccines, should they be needed in upcoming pandemics or outbreaks. It also bars requirements for "any treatment or procedure intended or designed to edit or alter human deoxyribonucleic acid (DNA) or the human genome," and "any mechanical or electronic device" that would be placed "under the skin."